Got this error, so had to uninstall JoomSEF until I can figure it out (have edited .htaccess as per documentation).

Not Found

The requested URL /property/view/homepage/layout/latest.tpl was not found on this server.

Additionally, a 404 Not Found error was encountered while trying to use an ErrorDocument to handle the request.

Apache/2.2.23 (Unix) mod_ssl/2.2.23 OpenSSL/1.0.0-fips mod_auth_passthrough/2.1 mod_bwlimited/1.4 FrontPage/5.0.2.2635 PHP/5.3.20 Server at www.mysite.co.uk Port 80